There are multiple methods of mass spectrometry and ionization. However, most of these methods are not suitable for organometallic/elementorganic samples, since inert application methods and soft ionization are usually necessary. In these cases, the liquid injection field desorption ionization mass spectrometry (LIFDI-MS) method has proven effective. Samples are introduced through a capillary from a sealed vial with a septum, and the ionization method itself is one of the softest available. For more information on LIFDI-MS I recommend reading this website (external link).

To prepare a sample in a glovebox I recommend using these small vials with a crimpable septum cap (Figure 1).

A crimp tool is also needed for the caps (Figure 2).

To prepare your sample a solution of the substance must be prepared. For most cases toluene has proven to be a good allrounder. It has a high boiling point which is needed because solvents with a lower boiling point may evaporate early which can lead to a clogged cannula. Some substances, especially more polar ones may not be readily dissolved in toluene. In these cases one to a few drops of fluorobenzene proved to be helpful.